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KMID : 1141520210360010196
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Endocrinology and Metabolism
2021 Volume.36 No. 1 p.196 ~ p.200
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Overweight and Obesity are Risk Factors for Coronavirus Disease 2019: A Propensity Score-Matched Case-Control Study
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Ji Won-Jun
Lee Ru-Gyeom
Huh Kyung-Min
Kang Min-Sun
Hwang In-Cheol
Radnaabaatar Munkhzul
Lee Dae-Ho
Jung Jae-Hun
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Abstract
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Although obesity is a risk factor for infection, whether it has the same effect on coronavirus disease 2019 (COVID-19) need confirming. We conducted a retrospective propensity score matched case-control study to examine the association between obesity and COVID-19. This study included data from the Nationwide COVID-19 Registry and the Biennial Health Checkup database, until May 30, 2020. We identified 2,231 patients with confirmed COVID-19 and 10-fold-matched negative test controls. Overweight (body mass index [BMI] 23 to 24.9 kg/m2; adjusted odds ratio [aOR], 1.16; 95% confidence interval [CI], 1.1.03 to 1.30) and class 1 obesity (BMI 25 to 29.9 kg/m2; aOR, 1.27; 95% CI, 1.14 to 1.42) had significantly increased COVID-19 risk, while classes 2 and 3 obesity (BMI ≥30 kg/m2) showed similar but non-significant trend. Females and those <50 years had more robust association pattern. Overweight and obesity are possible risk factors of COVID-19.
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KEYWORD
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COVID-19, Obesity, Overweight, Infections
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